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Recommended Reading

 

Mitchison, T. J. (1989). "Mitosis: basic concepts." Curr Opin Cell Biol 1(1): 67-74.

A good overview, written before we learned too many details of spindle component chemistry, so it focuses on the big issues.

McIntosh, J. R. (2002). "Chromosome-microtubule interactions during mitosis." Annu Rev Cell Dev Biol 18: 193-219.

A review of the issues surrounding kinetochore-MT interaction written in the context of more recent information.

Cleveland, D. W., Y. Mao, et al. (2003). "Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling." Cell 112(4): 407-21.

A review that focuses on the biochemistry of kinetochores and the functions they must accomplish.

Cheeseman, I. M., et al. (2008). "KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates." Mol Biol Cell 19(2): 587-94.

A paper showing the importance of one particular kinetochore complex in the process of assembling functional kinetochore-MT interaction.

 

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