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Papers for Journal Club

Theriot, J.A., T.J. Mitchison, L.G. Tilney, D.A. Portnoy (1992). The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization. Nature 357: 257-60.

This is the first paper to closely examine the dynamics of actin polymerization during actin-based motility of Listeria.

Loisel, P.L., R. Boujemaa, D. Pantaloni, M. Carlier (1999). Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature 401: 613-6. This is the first reconstitution of actin-based motility. This paper helped to elucidate the mechanism of actin-based motility.

Parekh, S.H., O. Chaudhuri, J.A. Theriot, D.A. Fletcher (2005).  Loading history determines the velocity of actin-network growth.  Nature Cell Biology 7: 1219-23.  This paper shows how a cantilever can be used to measure actin polymerization forces.

 

Pollard, T.D. and G.G. Borisy (2003). Cell motility driven by assembly and disassembly of actin filaments. Cell 112: 453-65. A good review on the importance of actin dynamics in cell motility and the proteins that modulate this process.


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