Education Teaching Tools Mary Beckerle Papers for Journal Club
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Papers for Journal Club The first two papers contain many of the studies that are featured in the lecture.
Yoshigi M, Hoffman LM, Jensen CC, Yost HJ, Beckerle MC. Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement. J Cell Biol. 2005 Oct 24;171(2):209-15.
Hoffman LM, Jensen CC, Kloeker S, Wang CL, Yoshigi M, Beckerle MC. Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling. J Cell Biol. 2006 Feb 27;172(5):771-82.
These next two papers were published after the iBioseminars lecture was taped, and expand upon the role of zyxin in mechanotransduction.
Hiroaki Hirata, Hitoshi Tatsumi and Masahiro Sokabe. Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner. Journal of Cell Science 121, 2795-2804 (2008)
Hiroaki Hirata, Hitoshi Tatsumi, and Masahiro Sokabe. Zyxin emerges as a key player in the mechanotransduction at cell adhesive structures. Commun Integr Biol. 2008 Oct–Dec; 1(2): 192–195. |
